publications by categories in reversed chronological order.

The following are publications from my lab and members of my lab, reflecting areas of interest and previous work. For Houman Khosravani’s specific publications, full listing please see the following (database) links:


  1. Retrospective Analysis of the Integration of Palliative Care Into the Care of Stroke Patients Admitted to a Regional Stroke Center
    H. Khosravani, M. Mahendiran, B. Sivanandan, S. Gardner, G. Saposnik, J. Brookes, A. Berall, and G.A. Perri
    American Journal of Hospice and Palliative Care, 2024
  2. Sex-Based Analysis of Workflow and Outcomes in Acute Ischemic Stroke Patients Treated With Alteplase Versus Tenecteplase
    D.J. Kim, N. Singh, L. Catanese, A.Y.X. Yu, A.M. Demchuk, M.I. Lloret-Villas, Y. Deschaintre, S.B. Coutts, H. Khosravani, R. Appireddy, F. Moreau, G. Gubitz, and 23 more authors
    Stroke, 2024
  3. Quality of Life After Intravenous Thrombolysis for Acute Ischemic Stroke: Results From the AcT Randomized Controlled Trial
    T.T. Sajobi, O.I. Arimoro, A. Ademola, N. Singh, F. Bala, M.A. Almekhlafi, Y. Deschaintre, S.B. Coutts, S. Thirunavukkarasu, H. Khosravani, R. Appireddy, F. Moreau, and 43 more authors
    Stroke, 2024
  4. Intravenous tenecteplase compared with alteplase for minor ischaemic stroke: a secondary analysis of the AcT randomised clinical trial
    R. Nair, N. Singh, M. Kate, N. Asdaghi, R. Sarmiento, F. Bala, S.B. Coutts, M. Horn, A.Y. Poppe, H. Williams, A. Ademola, I. Alhabli, and 17 more authors
    Stroke and Vascular Neurology, 2024


  1. Machine-learning assisted swallowing assessment: a deep learning-based quality improvement tool to screen for post-stroke dysphagia
    Rami Saab, Arjun Balachandar, Hamza Mahdi, Eptehal Nashnoush, Lucas X. Perri, Ashley L. Waldron, Alireza Sadeghian, Gordon Rubenfeld, Mark Crowley, Mark I. Boulos, Brian J. Murray, and Houman Khosravani
    Frontiers in Neuroscience, 2023
  2. Evaluating Barriers and Tools to Optimize Resident Call Scheduling on Neurology In-Patient Services (P8-7.006)
    James Im, Charles Kassardjian, Houman Khosravani, and Sara Mitchell
    Tuesday, April 25, 2023
  3. Evaluating the Effectiveness of the SPIKES Model to Break Bad News - A Systematic Review.
    Meera Mahendiran, Herman Yeung, Samantha Rossi, Houman Khosravani, and Giulia-Anna Perri
    The American journal of hospice & palliative care, 2023
  4. Safety and Efficacy of Tenecteplase Compared With Alteplase in Patients With Large Vessel Occlusion Stroke: A Prespecified Secondary Analysis of the ACT Randomized Clinical Trial
    Fouzi Bala, Nishita Singh, Brian Buck, Ayoola Ademola, Shelagh B Coutts, Yan Deschaintre, Houman Khosravani, Ramana Appireddy, Francois Moreau, Stephen Phillips, Gord Gubitz, Aleksander Tkach, and 22 more authors
    JAMA Neurology, 2023
  5. FLAIR MRI biomarkers of the Normal‐Appearing Brain Matter (NABM) are related to APOE‐4 status and CSF markers Aβ42 and Tau
    Karissa Chan, Corinne E Fischer, Houman Khosravani, Sandra E Black, Pascal Tyrrell, Pejman Jabehdar Maralani, Alan R Moody, and April Khademi
    Alzheimer’s & Dementia, 2023
  6. Study of Rivaroxaban for Cerebral Venous Thrombosis: A Randomized Controlled Feasibility Trial Comparing Anticoagulation With Rivaroxaban to Standard-of-Care in Symptomatic Cerebral Venous Thrombosis
    Thalia S Field, Vanessa Dizonno, Mohammed A Almekhlafi, Fouzi Bala, Ibrahim Alhabli, Hubert Wong, Monica Norena, Maria Karina Villaluna, Princess King-Azote, Namali Ratnaweera, Steven Mancini, Stephen C Van Gaal, and 178 more authors
    Stroke, 2023
  7. Effect of Time to Thrombolysis on Clinical Outcomes in Patients with Acute Ischemic Stroke Treated with Tenecteplase Compared to Alteplase: Analysis from the AcT Randomized Controlled Trial
    Nishita Singh, Mohammed Almekhlafi, Fouzi Bala, Ayoola Ademola, Shelagh B. Coutts, Yan Deschaintre, Houman Khosravani, Brian Buck, Ramana Appireddy, Francois Moreau, Gord Gubitz, Aleksander Tkach, and 22 more authors
    medRxiv, 2023


  1. Alteplase Compared to Tenecteplase in patients with Acute Ischemic Stroke (AcT) Trial: Protocol for a Pragmatic Registry linked Randomized Clinical Trial
    Tolulope Sajobi, Nishita Singh, Mohammed A Almekhlafi, Brian Buck, Ayoola Ademola, Shelagh B Coutts, Yan Deschaintre, Houman Khosravani, Ramana Appireddy, Francois Moreau, Stephen Phillips, Gord Gubitz, and 22 more authors
    Stroke: Vascular and Interventional Neurology, 2022
  2. AcT Trial: Protocol for a Pragmatic Registry‐Linked Randomized Clinical Trial
    Tolulope Sajobi, Nishita Singh, Mohammed A Almekhlafi, Brian Buck, Ayoola Ademola, Shelagh B Coutts, Yan Deschaintre, Houman Khosravani, Ramana Appireddy, Francois Moreau, Stephen Phillips, Gord Gubitz, and 22 more authors
    Stroke: Vascular and Interventional Neurology, 2022
  3. Attitudes of Canadian stroke physicians regarding palliative care for patients with acute severe stroke: A national survey.
    Houman Khosravani, Meera Mahendiran, Sandra Gardner, Camilla Zimmermann, and Giulia-Anna Perri
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2022
  4. Early identification of NORSE and transfer to care setting with appropriate supports: A proposed algorithm.
    Sarah A Vinette, Gordon Bryan Young, and Houman Khosravani
    Frontiers in neurology, 2022
  5. Global Impact of the COVID-19 Pandemic on Stroke Volumes and Cerebrovascular Events: One-Year Follow-up
    Thanh N. Nguyen, Muhammad M. Qureshi, Piers Klein, Hiroshi Yamagami, Robert Mikulik, Anna Czlonkowska, Mohamad Abdalkader, Petra Sedova, Anvitha Sathya, Hannah C. Lo, Ossama Yassin Mansour, Husitha Reddy Vanguru, and 360 more authors
    Neurology, 2022


  1. Assessment of Discrepancies Between Follow-up Infarct Volume and 90-Day Outcomes Among Patients With Ischemic Stroke Who Received Endovascular Therapy
    Aravind Ganesh, Johanna M Ospel, Bijoy K Menon, Andrew M Demchuk, Ryan A McTaggart, Raul G Nogueira, Alexandre Y Poppe, Mohammed A Almekhlafi, Ricardo A Hanel, Götz Thomalla, Staffan Holmin, Volker Puetz, and 683 more authors
    JAMA Network Open, 2021
  2. Quality of anticoagulation using intravenous unfractionated heparin for cerebrovascular indications
    Tess Fitzpatrick, Courtney Wong, Cindy Shen, Peter Pham, Vincent Teo, Rita Selby, William Geerts, and Houman Khosravani
    Thrombosis Research, 2021
  3. Cholinesterase Inhibitor Use in Patients With Dementia Admitted to a Palliative Care Unit.
    Giulia-Anna Perri, Jessica Wilson, Sandra Gardner, Anna Berall, Anne Kirstein, and Houman Khosravani
    The American journal of hospice & palliative care, 2021
  4. Frequency selective neuronal modulation triggers spreading depolarizations in the rat endothelin-1 model of stroke
    Paolo Bazzigaluppi, James Mester, Illsung L Joo, Iliya Weisspapir, Adrienne Dorr, Margaret M Koletar, Tina L Beckett, Houman Khosravani, Peter Carlen, and Bojana Stefanovic
    Journal of Cerebral Blood Flow & Metabolism, 2021
  5. The clot thickens—enhanced integration of stroke and thrombosis training
    Stephanie Carlin, William Geerts, and Houman Khosravani
    Journal of Thrombosis and Thrombolysis, 2021
  6. Global impact of COVID-19 on stroke care
    Raul G. Nogueira, Mohamad Abdalkader, Muhammed M. Qureshi, Michael R. Frankel, Ossama Yassin Mansour, Hiroshi Yamagami, Zhongming Qiu, Mehdi Farhoudi, James E. Siegler, Shadi Yaghi, Eytan Raz, Nobuyuki Sakai, and 261 more authors
    International Journal of Stroke, 2021
  7. Global Impact of COVID-19 on Stroke Care and IV Thrombolysis
    Raul G. Nogueira, Muhammad M. Qureshi, Mohamad Abdalkader, Sheila Ouriques Martins, Hiroshi Yamagami, Zhongming Qiu, Ossama Yassin Mansour, Anvitha Sathya, Anna Czlonkowska, Georgios Tsivgoulis, Diana Aguiar de Sousa, Jelle Demeestere, and 450 more authors
    Neurology, 2021
  8. Team debriefs during the COVID-19 pandemic in long-term care homes: Essential elements
    Giulia-Anna Perri, Warren Harris Lewin, and Houman Khosravani
    Canadian Family Physician, 2021


  1. Protected Code Stroke: Hyperacute Stroke Management During the Coronavirus Disease 2019 (COVID-19) Pandemic.
    Houman Khosravani, Phavalan Rajendram, Lowyl Notario, Martin G Chapman, and Bijoy K Menon
    Stroke, 2020
  2. The Dysfunction is in the Details: Neurovascular Changes in COVID-19
    Houman Khosravani
    Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 2020
  3. The Code Stroke Handbook
    Andrew Micieli, Raed Joundi, Houman Khosravani, Julia Hopyan, and David J Gladstone
    The Code Stroke Handbook, 2020
  4. Symptom management and end-of-life care of residents with COVID-19 in long-term care homes.
    Houman Khosravani, Leah Steinberg, Nadia Incardona, Patrick Quail, and Giulia-Anna Perri
    Canadian family physician Medecin de famille canadien, 2020
  5. Response by Khosravani et al to Letter Regarding Article, “Protected Code Stroke: Hyperacute Stroke Management During the Coronavirus Disease 2019 (COVID-19) Pandemic”
    Houman Khosravani, Phavalan Rajendram, and Bijoy K Menon
    Stroke, 2020
  6. Modification to Neurology Residency Training: The Toronto Neurology COVID-19 Pandemic Experience
    Ryan T Muir, Priti Gros, Robert Ure, Sara B Mitchell, Charles D Kassardjian, Aaron Izenberg, Peter Tai, Houman Khosravani, and David K Chan
    Neurology: Clinical Practice, 2020
  7. The Virtual Neurologic Exam: Instructional Videos and Guidance for the COVID-19 Era
    Mariam Al Hussona, Monica Maher, David Chan, Jonathan A Micieli, Jennifer D Jain, Houman Khosravani, Aaron Izenberg, Charles D Kassardjian, and Sara B Mitchell
    Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 2020
  8. Pandemic Guidance for Stroke Centers Aiding COVID-19 Treatment Teams.
    Charles R Wira, Mayank Goyal, Andrew M Southerland, Kevin N Sheth, Norma D McNair, Houman Khosravani, Anne Leonard, Peter Panagos, and  Council, AHA/ASA Stroke Council Science Subcommittees: Emergency Neurovascular Care (ENCC), Telestroke and the Neurovascular Intervention Committees; and on behalf of the Stroke Nursing Science Subcommittee of the AHA/ASA Cardiovascular and Stroke Nursing
    Stroke, 2020
  9. Crisis Resource Management and High-Performing Teams in Hyperacute Stroke Care
    Phavalan Rajendram, Lowyl Notario, Cliff Reid, Charles R Wira, Jose I Suarez, Scott D Weingart, and Houman Khosravani
    Neurocritical Care, 2020
  10. Outcomes of Endovascular Thrombectomy for Basilar Artery Occlusion
    Christopher R Pasarikovski, Houman Khosravani, Leodante da Costa, Chinthaka Heyn, Stefano M Priola, Jerry C Ku, Sandra E Black, David J Gladstone, and Victor X D Yang
    Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 2020


  1. Proposed consensus definitions for new‐onset refractory status epilepticus (NORSE), febrile infection‐related epilepsy syndrome (FIRES), and related conditions
    Lawrence J. Hirsch, Nicolas Gaspard, Andreas Baalen, Rima Nabbout, Sophie Demeret, Tobias Loddenkemper, Vincent Navarro, Nicola Specchio, Lieven Lagae, Andrea O. Rossetti, Sara Hocker, Teneille E. Gofton, and 6 more authors
    Epilepsia, 2018
  2. A Survey of Knowledge and Attitudes of Nurses About Pain Management in End-Stage Liver Disease in a Geriatric Palliative Care Unit
    Giulia-Anna Perri, Herman Yeung, Yoel Green, Abby Bezant, Carman Lee, Anna Berall, Jurgis Karuza, and Houman Khosravani
    American Journal of Hospice and Palliative Medicine®, 2018


  1. Complications of end-stage liver disease.
    Giulia-Anna Perri, and Houman Khosravani
    Canadian family physician Medecin de famille canadien, 2016
  2. Attributes and outcomes of end stage liver disease as compared with other noncancer patients admitted to a geriatric palliative care unit
    Giulia-Anna Perri, Shannon Bunn, Yeon Ji Oh, Altaf Kassam, Anna Berall, Jurgis Karuza, and Houman Khosravani
    Annals of Palliative Medicine, 2016


  1. Association of mortality in stage 3 chronic kidney disease with variability in estimated glomerular filtration rate
    Houman Khosravani, David M J Naimark, and Sunnybrook Nephrology Journal Club
    Kidney International, 2013


  1. Time–Frequency Phase Analysis of Ictal EEG Recordings With the S-Transform
    C Robert Pinnegar, Houman Khosravani, and Paolo Federico
    IEEE Transactions on Biomedical Engineering, 2009
  2. Occurrence and adverse effect on outcome of hyperlactatemia in the critically ill.
    Houman Khosravani, Reza Shahpori, H Thomas Stelfox, Andrew W Kirkpatrick, and Kevin B Laupland
    Critical care (London, England), 2009
  3. Spatial localization and time-dependant changes of electrographic high frequency oscillations in human temporal lobe epilepsy
    Houman Khosravani, Nikhil Mehrotra, Michael Rigby, Walter J Hader, C Robert Pinnegar, Neelan Pillay, Samuel Wiebe, and Paolo Federico
    Epilepsia, 2009
  4. Prion protein attenuates excitotoxicity by inhibiting NMDA receptors
    Houman Khosravani, Yunfeng Zhang, Shigeki Tsutsui, Shahid Hameed, Christophe Altier, Jawed Hamid, Lina Chen, Michelle Villemaire, Zenobia Ali, Frank R. Jirik, and Gerald W. Zamponi
    Journal of Cell Biology, 2009


  1. Cellular prion protein null mice display normal AMPA receptor mediated long term depression
    Houman Khosravani, Yunfeng Zhang, and Gerald W Zamponi
    Prion, 2008
  2. Specific Lipids Supply Critical Negative Spontaneous Curvature—An Essential Component of Native Ca2+-Triggered Membrane Fusion
    Matthew A Churchward, Tatiana Rogasevskaia, David M Brandman, Houman Khosravani, Phillip Nava, Jeffrey K Atkinson, and Jens R Coorssen
    Biophysical Journal, 2008
  3. Prion protein attenuates excitotoxicity by inhibiting NMDA receptors.
    Houman Khosravani, Yunfeng Zhang, Shigeki Tsutsui, Shahid Hameed, Christophe Altier, Jawed Hamid, Lina Chen, Michelle Villemaire, Zenobia Ali, Frank R Jirik, and Gerald W Zamponi
    The Journal of cell biology, 2008


  1. Modulation of NMDA receptors by prion proteins
    Houman Khosravani, Yunfeng Zhang, Shigeki Tsutsui, Shahid Hameed, Jawed Hamid, Christophe Altier, Frank R Jirik, and Gerald W Zamponi
    Clinical & Investigative Medicine, 2007
  2. Extended spectrum of idiopathic generalized epilepsies associated with CACNA1H functional variants
    Sarah E Heron, Houman Khosravani, Diego Varela, Chris Bladen, Tristiana C Williams, Michelle R Newman, Ingrid E Scheffer, Samuel F Berkovic, John C Mulley, and Gerald W Zamponi
    Annals of Neurology, 2007


  1. The effects of high-frequency oscillations in hippocampal electrical activities on the classification of epileptiform events using artificial neural networks
    Alan W L Chiu, Shokrollah S Jahromi, Houman Khosravani, Peter L Carlen, and Berj L Bardakjian
    Journal of Neural Engineering, 2006
  2. Voltage-Gated Calcium Channels and Idiopathic Generalized Epilepsies
    Houman Khosravani, and Gerald W. Zamponi
    Physiological Reviews, 2006
  3. ORL1 receptor–mediated internalization of N-type calcium channels
    Christophe Altier, Houman Khosravani, Rhian M Evans, Shahid Hameed, Jean B Peloquin, Brian A Vartian, Lina Chen, Aaron M Beedle, Stephen S G Ferguson, Alexandre Mezghrani, Stefan J Dubel, Emmanuel Bourinet, and 2 more authors
    Nature Neuroscience, 2006
  4. Functional analysis of Ca3.2 T-type calcium channel mutations linked to childhood absence epilepsy.
    Jean B Peloquin, Houman Khosravani, Wendy Barr, Chris Bladen, Rhian Evans, Janette Mezeyova, David Parker, Terrance P Snutch, John E McRory, and Gerald W Zamponi
    Epilepsia, 2006
  5. Role of Angiotensin II Type 1A Receptor Phosphorylation, Phospholipase D, and Extracellular Calcium in Isoform-specific Protein Kinase C Membrane Translocation Responses*
    Aleksandra Policha, Noriko Daneshtalab, Lina Chen, Lianne B. Dale, Christophe Altier, Houman Khosravani, Walter G. Thomas, Gerald W. Zamponi, and Stephen S.G. Ferguson
    Journal of Biological Chemistry, 2006
  6. Dynamics of epileptic phenomena determined from statistics of ictal transitions.
    Piotr Suffczynski, Fernando H Lopes da Silva, Jaime Parra, Demetrios N Velis, Brigitte M Bouwman, Clementina M van Rijn, Peter van Hese, Paul Boon, Houman Khosravani, Miron Derchansky, Peter Carlen, and Stiliyan Kalitzin
    IEEE transactions on bio-medical engineering, 2006


  1. Effects of Cav3.2 channel mutations linked to idiopathic generalized epilepsy
    Houman Khosravani, Christopher Bladen, David B Parker, Terrance P Snutch, John E McRory, and Gerald W Zamponi
    Annals of Neurology, 2005
  2. The Arg473Cys-neuroligin-1 mutation modulates NMDA mediated synaptic transmission and receptor distribution in hippocampal neurons
    Houman Khosravani, Christophe Altier, Gerald W Zamponi, and Michael A Colicos
    FEBS Letters, 2005
  3. Increased High‐frequency Oscillations Precede in vitro Low‐Mg2+ Seizures
    Houman Khosravani, C. Robert Pinnegar, J. Ross Mitchell, Berj L. Bardakjian, Paolo Federico, and Peter L. Carlen
    Epilepsia, 2005
  4. Prediction of seizure onset in an in-vitro hippocampal slice model of epilepsy using Gaussian-based and wavelet-based artificial neural networks.
    Alan W L Chiu, Sarit Daniel, Houman Khosravani, Peter L Carlen, and Berj L Bardakjian
    Annals of biomedical engineering, 2005


  1. A subharmonic dynamical bifurcation during in vitro epileptiform activity
    Jose L. Perez Velazquez, and Houman Khosravani
    Chaos: An Interdisciplinary Journal of Nonlinear Science, 2004
  2. Gating Effects of Mutations in the Cav3.2 T-type Calcium Channel Associated with Childhood Absence Epilepsy
    Houman Khosravani, Christophe Altier, Brett Simms, Kevin S Hamming, Terrance P Snutch, Janette Mezeyova, John E McRory, and Gerald W Zamponi
    Journal of Biological Chemistry, 2004


  1. Time response of interstitial fluid pressure measurements in cervix cancer.
    Houman Khosravani, Brige Chugh, Michael F Milosevic, and Kenneth H Norwich
    Microvascular research, 2003
  2. Video-EEG evidence of lateralized clinical features in primary generalized epilepsy with tonic-clonic seizures.
    Leanne Casaubon, Bernd Pohlmann-Eden, Houman Khosravani, Peter L Carlen, and Richard Wennberg
    Epileptic disorders : international epilepsy journal with videotape, 2003


  1. Type III intermittency in human partial epilepsy
    J L Perez Velazquez, Houman Khosravani, Andres Lozano, Berj L Bardakjian, Peter L Carlen, and Richard Wennberg
    European Journal of Neuroscience, 1999


  1. CO2 uptake mechanism in Eremosphaera viridis
    Jason S T Deveau, Houman Khosravani, Roger R Lew, and Brian Colman
    Canadian Journal of Botany, 1998